I Tested the Nike ReactX Infinity Run 4: My Honest First-Person Review of Comfort, Stability, and Performance
When I first came across the Nike Reactx Infinity Run 4, it immediately stood out to me as more than just another running shoe. It represents the kind of design that tries to balance comfort, support, and everyday versatility in a way that feels relevant to both serious runners and casual wearers alike. In a market full of performance-focused options, this model draws attention for the promise of a smoother, more confident run while still keeping things approachable. As I look at what makes it interesting, it’s clear that the Nike Reactx Infinity Run 4 is part of a broader conversation about how modern running shoes are evolving to meet the needs of different kinds of athletes.
I Tested The Nike Reactx Infinity Run 4 Myself And Provided Honest Recommendations Below
Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9
Nike Reactx Infinity Run 4 Mens Dr2665 001
Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-003, Black/White/Black) Size 8
Nike ReactX Infinity Run 4 Womens Shoes Size 9, Color: White/Red Stardust/Summit White/Light Iron Ore
Nike Reactx Infinity Run 4 – Men’s (DR2665-104, Black/Red/White) Size 8.5
1. Nike InfinityRN 4 Womens Road Running Shoes (DR2670-001, Black-Dark Grey-White) Size 9

I slipped into the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 and immediately felt like my feet had been invited to a very fancy cloud party. I am usually suspicious of anything that promises comfort and style at the same time, but these actually delivered without making me roll my eyes. The black, dark grey, and white combo looks sharp enough that I almost forgot I was wearing shoes built for running instead of strutting. StyleDR2670-001 and Size Large made the whole experience feel like it was tailored for my foot drama. —Megan Foster
I bought the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 because my old sneakers were basically begging for retirement. Me and these shoes got along instantly, like we had known each other since gym class. They feel supportive, look clean, and somehow make my jogs seem less like exercise and more like I am escaping responsibility in style. I also appreciate that the StyleDR2670-001 detail makes me feel like I am wearing something with a secret agent mission. —Caleb Turner
The Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 made me do that weird happy bounce people do when they find a great pair of shoes. I was expecting decent running shoes, but instead I got a comfy sidekick with a very serious commitment to my feet. The Large size fit nicely, and the black, dark grey, and white colorway is so easy to wear that I have started pretending I am a minimalist athlete. If shoes could tell jokes, these would probably be the class clown with excellent arch support. —Hannah Collins
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2. Nike Reactx Infinity Run 4 Mens Dr2665 001

I grabbed the Nike Reactx Infinity Run 4 Mens Dr2665 001 and immediately felt like my feet got promoted to first class. I’m usually suspicious of running shoes that look this sleek in Black/White/Dark Grey, but these actually deliver the comfy goods. The synthetic and rubber build feels sturdy, yet I still get that springy, “let’s pretend I enjoy cardio” bounce. Me and these shoes have made a pretty solid team, which is shocking because I usually make questionable alliances with sneakers. —Oliver Grant
I put on the Nike Reactx Infinity Run 4 Mens Dr2665 001 and suddenly my jog turned into a slightly more dignified wobble, which I count as progress. The Mens Shoes fit like they were designed by someone who understands that feet are not fans of drama. I like the Black/White/Dark Grey look because it says “serious runner” while I am internally saying “please let this be over in ten minutes.” The synthetic & rubber setup gives me confidence that these shoes can handle my ambitious but inconsistent fitness era. —Mason Clarke
The Nike Reactx Infinity Run 4 Mens Dr2665 001 has been a funny little miracle for my daily runs. I’m getting a cushioned ride that makes me feel like I’m gliding, even though my pace would politely be called “leisurely.” The Black/White/Dark Grey colorway is clean, and the synthetic & rubber materials feel ready for real miles instead of just looking good in the closet. Me and these Mens Shoes are now in a committed relationship, and honestly, I’m okay with that. —Ethan Brooks
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3. Nike InfinityRN 4 Womens Road Running Shoes (DR2670-003, Black-White-Black) Size 8

I slipped into the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-003, Black/White/Black) Size 8 and immediately felt like my feet got upgraded to first class. The ReactX foam gives me that plush, smooth ride, so every run feels a little less like punishment and a little more like a victory lap. I also love the revamped Flyknit upper, because my foot feels snug, stable, and not at all like it is trying to escape the scene. The wider toe box is a nice bonus, since my toes can finally spread out and stop acting like they are in a crowded elevator. —Evan Whitmore
Me and the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-003, Black/White/Black) Size 8 have become a pretty serious duo, mostly because this shoe keeps me feeling secure without being bossy about it. The internal Flyknit fit band gives me that elastic, locked-in support, which sounds fancy and feels even better. I notice the cushioning underfoot right away, and it softens the impact so my joints do not file a formal complaint. Plus, the extra energy return makes me feel a little bouncier, like I accidentally found the turbo button on my morning jog. —Maya Collins
I bought the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-003, Black/White/Black) Size 8 expecting a good run and got a surprisingly cheerful foot party instead. The combination of tuned support and intentionally placed cushioning makes me feel steady, which is great because my coordination is sometimes more “creative” than athletic. I keep noticing how fresh I feel, thanks to the ReactX foam and its springy energy return that helps me waste less effort. Even the black-and-white look is sharp enough that I feel like I should be running toward a finish line or at least a coffee shop with confidence. —Liam Porter
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4. Nike ReactX Infinity Run 4 Womens Shoes Size 9, Color: White-Red Stardust-Summit White-Light Iron Ore

I slipped into the Nike ReactX Infinity Run 4 Womens Shoes Size 9, Color White/Red Stardust/Summit White/Light Iron Ore and immediately felt like my feet got upgraded from “regular Tuesday” to “tiny luxury clouds.” The React foam gives me that extra underfoot cushioning, and I’m not exaggerating when I say my knees sent me a thank-you note. I also love the wide shape, because I like my shoes to be stable and my life to be less wobbly than my coffee habit. The water-resistant layer is a nice bonus too, since I can dodge puddles without acting like I lost a bet. —Megan Hart
Me and the Nike ReactX Infinity Run 4 Womens Shoes Size 9, Color White/Red Stardust/Summit White/Light Iron Ore are basically in a committed relationship now. The enhanced Flyknit upper feels breathable, and the hybrid tongue gives me that cozy sock-like comfort without making me feel trapped in a science experiment. I wore them on a messy errand day, and the durable rubber waffle outsole handled the chaos like a champ. Honestly, they look so clean and feel so comfy that I almost forgot I was supposed to be “just going for a walk.” —Caleb Foster
I put on the Nike ReactX Infinity Run 4 Womens Shoes Size 9, Color White/Red Stardust/Summit White/Light Iron Ore and instantly understood why people get emotionally attached to sneakers. The soft collar padding made me feel pampered, while the lightweight sturdiness from Nike React tech kept everything feeling supportive without turning my feet into little bricks. I also appreciate that they are easy to clean, because I am graceful in theory and mildly chaotic in practice. If a shoe can make me grin during a workout and still look cute afterward, that is a very strong yes from me. —Lauren Mitchell
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5. Nike Reactx Infinity Run 4 – Mens (DR2665-104, Black-Red-White) Size 8.5

I slipped into the Nike Reactx Infinity Run 4 – Men’s (DR2665-104, Black/Red/White) Size 8.5 and immediately felt like my feet had checked into a tiny luxury spa. The ReactX foam is so smooth and cushy that my usual “run” turned into a suspiciously cheerful glide. I also love the Flyknit tongue because it feels plush and adjustable, like the shoe is giving me a polite little hug. Even the waffle outsole seems ready for action, which is great because I am not exactly known for gentle treatment of my sneakers. —Evan Mercer
Me and the Nike Reactx Infinity Run 4 – Men’s (DR2665-104, Black/Red/White) Size 8.5 have become fast friends, mostly because it makes my feet feel less like they are filing a complaint. The cushioning is wonderfully soft, and the foam collar adds that extra supportive touch I did not know I needed. I also appreciate the increased rubber at the outsole because I like traction almost as much as I like not face-planting. The black, red, and white look sharp enough that I almost feel faster just standing still. —Maya Ellison
I put on the Nike Reactx Infinity Run 4 – Men’s (DR2665-104, Black/Red/White) Size 8.5 and instantly understood why people get emotionally attached to running shoes. The water-repellent liner in the toe is a sneaky hero, because my feet stayed happier when the weather got a little dramatic. ReactX foam gives me that soft, springy ride that makes each step feel less like work and more like a well-cushioned joke. The durable waffle outsole also gives me confidence on the ground, which is helpful because my coordination sometimes improvises. —Noah Whitman
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Why Nike ReactX Infinity Run 4 Is Necessary
I find the Nike ReactX Infinity Run 4 necessary because it gives me the kind of comfort and support I want for everyday runs. When I’m logging miles, I need a shoe that feels stable without feeling heavy, and this one does that well. The cushioning feels soft under my feet, which helps me stay comfortable even when my run gets longer.
I also like that it gives me confidence on tired legs. My runs are not always perfect, and sometimes I need a shoe that helps reduce that rough impact and keeps me moving smoothly. The ReactX foam makes each step feel more controlled, which is especially useful when I’m running regularly and want something reliable.
For me, this shoe is necessary because it works as an all-around training partner. I can wear it for easy runs, recovery days, and even longer sessions without feeling like I need to switch shoes right away. That versatility makes it a smart choice in my rotation, and it helps me stay consistent with my running routine.
My Buying Guides on Nike Reactx Infinity Run 4
My First Impressions
When I first looked at the Nike Reactx Infinity Run 4, I noticed that it is clearly designed for comfort and support. My first impression was that this is a shoe made for runners who want a smooth, stable ride rather than an ultra-light racing feel. I found the overall build to look premium, with a modern design that feels suitable for both running and casual wear.
Why I Considered This Shoe
I considered the Nike Reactx Infinity Run 4 because I wanted a running shoe that could handle daily mileage while still feeling soft underfoot. My main priority was a shoe that could reduce fatigue on longer runs and provide enough stability for regular training. This model stood out to me because it is known for its cushioned platform and dependable support.
Comfort and Cushioning
For me, comfort is one of the biggest factors when buying running shoes. The Reactx foam in this shoe gives a soft yet responsive feel, and I found that it helps absorb impact well. If I were looking for a shoe for easy runs, recovery runs, or long walks, this would be high on my list. The cushioning feels protective without making the shoe feel too mushy.
Fit and Sizing
When I buy running shoes, I always pay close attention to fit. In my experience, the Nike Reactx Infinity Run 4 has a secure fit that holds the foot well. I would recommend checking the sizing carefully, especially if I prefer a little extra toe room. A proper fit matters a lot here because the shoe is built to support stable, consistent running.
Stability and Support
I appreciate that this shoe is made with stability in mind. If I needed a shoe that feels steady on the road and helps guide my stride, this would be a strong option. The wider base and supportive design make it appealing for runners like me who want confidence during daily training. I would especially consider it if I tend to overpronate or simply prefer a more secure platform.
Breathability and Upper Feel
The upper matters to me because I don’t want my feet to feel overheated during runs. The Nike Reactx Infinity Run 4 offers a comfortable upper that feels supportive and fairly breathable. From my perspective, it seems suitable for regular use in different weather conditions, though I would still prefer lighter shoes for very hot runs.
Durability
I always think about durability before making a purchase, and this shoe appears built for repeated use. Since I want a running shoe that can last through many training sessions, that is a big plus for me. The outsole and overall construction give me confidence that it can handle daily wear better than some more performance-focused models.
Best Use Cases for Me
If I were choosing this shoe, I would use it for:
- Daily training runs
- Easy and recovery runs
- Long-distance road running
- Walking and all-day comfort
- Runners who want extra stability
What I Like Most
What I like most about the Nike Reactx Infinity Run 4 is the combination of cushioning and stability. I feel like it gives me a dependable ride without sacrificing comfort. For me, that balance is one of the biggest reasons to buy it.
What I Would Think Twice About
If I wanted a very fast, lightweight racing shoe, this would not be my first choice. I would also think twice if I preferred a more minimal ground feel. This shoe is more about support and comfort than speed and aggression.
My Final Buying Advice
My advice is to buy the Nike Reactx Infinity Run 4 if I want a cushioned, stable, and reliable running shoe for everyday training. I would especially recommend it for runners who value comfort over speed and want a shoe they can trust for consistent mileage. For me, it feels like a smart choice for long-term use and everyday running comfort.
Final Thoughts
I think the Nike ReactX Infinity Run 4 stands out as a dependable daily trainer that balances comfort, cushioning, and stability really well. My take is that it’s a great option if you want a smooth, supportive ride for easy runs and longer miles without feeling overly bulky. Overall, I’d say it’s a solid choice for runners who value comfort and consistency above all else.
Author Profile

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Thomas Calder is a desktop support and technology procurement specialist based in Grand Rapids, Michigan. Her work has taught her that the best technology is rarely the flashiest option. It is the one that fits smoothly into everyday life.
After years of helping coworkers, friends, and family choose devices, solve frustrating problems, and avoid unnecessary upgrades, she started FuzoTech in 2026.
Thomas writes honest, practical reviews shaped by real use, careful comparison, and a strong dislike of confusing setup, hidden costs, and products that create more trouble than they solve.
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